Circulating tumor cells (CTCs) are an early warning sign of cancer
Tumors begin to grow up as many as 5 to 10 years before they are detected. Circulating Tumor Cells (CTCs) enter the bloodstream from the earliest days of tumor development.
Rarecells’ proprietary ISET® (Isolation by Size of Tumor cells) device is a highly accurate, non-invasive liquid biopsy technology, designed to detect cancer earlier and prevent metastases.
ISET® is a certified CE-Mark In Vitro Diagnostic (CE-IVD) platform with the CE-Mark validated unparalleled ability to extract down to a single cancer cell from among 50 billion blood cells in a 10 ml blood sample.
Our technology is designed to detect cancer earlier
Many liquid biopsy tests are based on circulating tumor DNA (ctDNA). ctDNA is easier to isolate than CTCs, but has been consistently reported to have have low sensitivity at early stages of cancer.
Rarecells’ next-generation ISET® technology allows CTC-DNA to be obtained with the highest sensitivity, providing high quality, enriched tumor CTC-DNA for accurate liquid biopsy tests. Furthermore, the new ISET® process optimizes the extraction of CTC-DNA and ctDNA from the same stabilized blood sample in standard Streck(r) tubes.
The combined analysis of both CTC-DNA and ctDNA has the potential to dramatically improve sensitivity and provides a more complete solution for detection of early-stage cancer and cancer recurrence.

A strong base of published evidence
ISET®’s groundbreaking sensitivity and specificity have been established through 110+ high-level, peer-reviewed and independent scientific publications. Studies demonstrated the efficacy and utility of tests using ISET®-collected cells in early detection of cancer, cancer prognosis, and non-invasive theranostics.
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