ISET® TECHNOLOGY



ISET®, Isolation by SizE of Tumor Cells, is based on the antibody-independent whole blood filtration approach for CTC and micro-emboli isolation. The solution relies on the larger size of all types of CRC as compared to the majority of leukocytes. ISET system successfully captures CTC that are presenting, by definition, heterogeneous phenotypic profiles.

SIMPLE WORKFLOW

  • 10 mL blood draw collected in EDTA or STECK tubes
  • Sample mixed with application-specific buffer for integrity of CTC and DNA structure
  • Sample processed on the ISET© Device pressure-controlled filtration system
  • Fixed cells: Multiplexed downstream processing from the 10 spots of the membrane
  • Living cells: collected in 15mL tube

SIMPLE WORKFLOW

  • 10 mL blood draw collected in EDTA or STECK tubes
  • Sample mixed with application-specific buffer for integrity of CTC and DNA structure
  • Sample processed on the ISET© Device pressure-controlled filtration system
  • Fixed cells: Multiplexed downstream processing from the 10 spots of the membrane
  • Living cells: collected in 15mL tube

ISET® BENEFITS

  • Collection of cells that cannot be detected with antibody collection technics
  • All solid cancers
  • Detection threshold of one circulating cell per 10 ml of blood
  • Deliver CTC and cfDNA from a single 10mL blood draw
  • Specific buffer for living and fixed cells application to preserve structural cells integrity
  • Living cells and fixed cells
  • Compatibility with downstream processing from cytology examination to DNA gene mutation detection via cell culture
  • ISET® Device is CE IVD
  • Vast scientific literature backup
ISET blood filtration machine

ISET® BENEFITS

  • Collection of cells that cannot be detected with antibody collection technics
  • All solid cancers
  • Detection threshold of one circulating cell per 10 mL of blood
  • Deliver CTC and cfDNA from a single 10mL blood draw
  • Specific buffer for living and fixed cells application to preserve structural cells integrity
  • Living cells and fixed cells
  • Compatibility with downstream processing from cytology examination to DNA gene mutation detection via cell culture
  • ISET® Device is CE IVD
  • Vast scientific literature backup
ISET blood filtration machine

STRONG BASE OF PUBLISHED EVIDENCES

>80 high-level, peer-reviewed and independent scientific publications covering more than 2000 cancer patients and 1000 healthy subjects as controls.

ISET® has proven its unparalleled sensitivity, specificity and clinical value in patients with all types of solid cancers and the main types of leukemia.

Studies demonstrated potential benefits of test derived from ISET® collected cells in early detection of cancer, cancer prognosis, and non-invasive theranostics.

STRONG BASE OF PUBLISHED EVIDENCES

>80 high-level, peer-reviewed and independent scientific publications covering more than 2000 cancer patients and 1000 healthy subjects as controls.

ISET® has proven its unparalleled sensitivity, specificity and clinical value in patients with all types of solid cancers and the main types of leukemia.

Studies demonstrated potential benefits of test derived from ISET® collected cells in early detection of cancer, cancer prognosis, and non-invasive theranostics.

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It’s easy: all we need is your name, email & preferences to send you your brochure(s) !