CTC IN ANIMAL MODEL



Animal model are useful to study tumor dissemination processes such as functional mediators of survival, formation and growth of metastasis from CTCs; and for preclinical drug development where CTCs could be used as a surrogate but reliable endpoint.

process blood from a wide variety of animals

Laget et al. 2017 Plos One

The ISET® technology is so flexible that it is not only capable of filtering human blood but also blood from many animal models. So far, blood samples from mouse, rat (Lelièvre L. et al, Int J Gynecol Cancer 2004), pig, horse, dog and chimpanzee have been treated using the ISET® technology.

ISET® is also compatible with blood collected by retro-orbital puncture. ISET could be adapted and personalized for any animal species. Please contact us for more information.

Contact us for more information about filtering blood from animal models and adapting the protocol according to the animal species.

The image shows clusters of cells with malignant features observed in the blood of two MMTV-PyMT mice (breast cancer model). Blood was withdrawn by cardiac punction and processed by ISET®. 

Laget et al. 2017 Plos One

The ISET® technology is so flexible that it is not only capable of filtering human blood but also blood from many animal models. So far, blood samples from mouse, rat (Lelièvre L. et al, Int J Gynecol Cancer 2004), pig, horse, dog and chimpanzee have been treated using the ISET® technology.

ISET® is also compatible with blood collected by retro-orbital puncture. ISET could be adapted and personalized for any animal species. Please contact us for more information.

Contact us for more information about filtering blood from animal models and adapting the protocol according to the animal species.

The image shows clusters of cells with malignant features observed in the blood of two MMTV-PyMT mice (breast cancer model). Blood was withdrawn by cardiac punction and processed by ISET®. 

To the left: Blood from MMTV-PyVT mutant mouse (breast cancer model) was withdrawn by cardiac punction and processed by ISET®. ISET® is also compatible with blood collected by retro-orbital puncture.

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