An independently funded, 6-year-long monocentric study, published in 2014, demonstrated that ISET® was able to make a very early diagnosis of lung cancer.
254 patients including 168 patients with COPD followed by ISET and low dose CT-scan screening
- 5 of 168 presented CCC detected by ISET
- Per 10 mL of blood, 19 to 67 isolated CCC and 1 to 3 CCM, Vimentin expression
In these 5 patients:
- CT-scan detected a lung nodule 1 to 4 years after CCC detection by ISET leading to surgical resection and early diagnosis of Lung Cancer (stage 1A)
- Follow up of the 5 patients at 18 months after surgery: no tumor recurrence, no CCC.
542 individuals tested with ISET®: 277 patients with cancer and 256 individuals at risk of developping cancer.
100% of cancer patients presented CCC
132 at risk individuals (50%) presented CCC
10 months follow-up of CCC-positive at risk individuals:
20% of at risk individuals diagnosed with early stage cancers by imaging techniques.